When John Herrington was born in 1670, in Talbot, Maryland, United States, his father, Richard Herrington, was 20 and his mother, Maria Schermerhorn, was 25. He married Anna Sarah Phillips on 2 September 1712, in Saint Peters Parish, Talbot, Maryland, United States. They were the parents of at least 7 sons and 1 daughter. He died in 1737, in Saint Peters Parish, Talbot, Maryland, United States, at the age of 67.