When John Inwardby was born on 12 October 1449, in Quainton, Buckinghamshire, England, United Kingdom, his father, Nicholas Iwardby, was 27 and his mother, Elizabeth Hampden, was 23. He married Lady Joan Brudenell about 1474, in Quainton, Buckinghamshire, England. They were the parents of at least 3 daughters. He died on 22 August 1485, in Dadlington, Leicestershire, England, United Kingdom, at the age of 35, and was buried in Dadlington, Leicestershire, England, United Kingdom.