When James Sackett Reynolds was born on 6 July 1700, in Greenwich, Fairfield, Connecticut Colony, British Colonial America, his father, Capt James Reynolds I, was 26 and his mother, Sarah Smith, was 20. He married Phebe Fowler on 24 May 1731, in Greenwich, Fairfield, Connecticut Colony, British Colonial America. They were the parents of at least 2 sons and 8 daughters. He died on 2 June 1773, in Amenia, Dutchess, New York Colony, British Colonial America, at the age of 72, and was buried in Smithfield, Dutchess, New York Colony, British Colonial America.