When Frank James Scearce was born on 10 May 1904, in Danville, Virginia, United States, his father, Benjamin Wesley Scearce, was 32 and his mother, Emma Jane Burnett, was 26. He married Martha Beatrice Pruett on 7 December 1923, in Danville, Virginia, United States. They were the parents of at least 1 son and 1 daughter. He lived in Winston Township, Forsyth, North Carolina, United States in 1910 and Pelham, Caswell, North Carolina, United States in 1920. He died on 4 June 1955, in Norfolk, Virginia, United States, at the age of 51, and was buried in Highland Burial Park, Danville, Virginia, United States.