When Packard Bruce was born on 2 October 1791, in New York, United States, his father, John Bruce III, was 45 and his mother, Temperance Elizabeth Packard, was 42. He married Dolly Searle on 12 September 1820, in New York, United States. They were the parents of at least 5 sons and 3 daughters. He lived in Centerville, Allegany, New York, United States in 1850 and Cuba, Cuba, Allegany, New York, United States in 1855. He died on 12 February 1856, in New York, United States, at the age of 64, and was buried in Cuba, Cuba, Allegany, New York, United States.