When Lydia Little was born on 10 October 1790, in Scituate, Plymouth, Massachusetts, United States, her father, James Little, was 31 and her mother, Lydia Young, was 31. She married Elisha James on 19 May 1808. They were the parents of at least 6 sons and 4 daughters. She died on 5 November 1851, in Scituate, Plymouth, Massachusetts, United States, at the age of 61, and was buried in Scituate, Plymouth, Massachusetts, United States.