When Jesse Clower was born in 1785, in Orange, North Carolina, United States, his father, George Michael Clower, was 50 and his mother, Elizabeth Catherine Morgan, was 56. He married Matilda Hansford on 13 August 1811, in Forsyth, Monroe, Georgia, United States. They were the parents of at least 3 sons and 1 daughter. He registered for military service in 1812. He died in 1832, in Monroe, Georgia, United States, at the age of 47.