When Hendirk Van Holthe was born in 1465, his father, Arent Van Holte, was 15 and his mother, Fenne Morre, was 15. He married Foijsche Greve about 1485. They were the parents of at least 1 son and 1 daughter. He died in 1539, in Elburg, Gelderland, Netherlands, at the age of 74.