When Mary Elizabeth Upshaw was born in 1803, in Oglethorpe, Georgia, United States, her father, Forrester Upshaw, was 31 and her mother, Ann Faulkner, was 32. She married Edward F Manery on 20 August 1820, in Madison, Georgia, United States. They were the parents of at least 4 sons and 10 daughters. She lived in McMinn, Tennessee, United States for about 10 years. She died about 1865, in Agnos, Fulton, Arkansas, United States, at the age of 62, and was buried in Fulton, Arkansas, United States.