When Joseph Liles was born on 9 April 1792, in Oconee, South Carolina, United States, his father, David Carlile, was 32 and his mother, Deborah Dogen, was 26. He married Zillah Ward in 1838, in Old Madison, Oconee, South Carolina, United States. He lived in Tugaloo Township, Oconee, South Carolina, United States in 1870. He died on 26 July 1870, in Oconee, South Carolina, United States, at the age of 78, and was buried in Oconee, South Carolina, United States.