When Reuben Fowler was born on 3 September 1753, in Fox Meadow, Westchester, New York Colony, British Colonial America, his father, Reuben Fowler, was 33 and his mother, Jane Valentine, was 29. He married Martha Drake about 1773, in Yorktown, Westchester, New York, United States. They were the parents of at least 5 sons and 3 daughters. He died on 1 February 1832, in White Plains, Westchester, New York, United States, at the age of 78, and was buried in Old Van Cortlandtville Cemetery, Van Cortlandtville, Cortlandt, Westchester, New York, United States.