When Jose Isidro Velasquez was born on 15 May 1916, in Tierra Amarilla, Rio Arriba, New Mexico, United States, his father, Donicio Velasquez, was 43 and his mother, Maria Francisca Martinez, was 40. He married Maria Geronima Antonia Sanchez on 27 June 1938. They were the parents of at least 1 daughter. He lived in Election Precinct 17 Tierra Amarilla, Rio Arriba, New Mexico, United States for about 10 years. He died on 20 August 1990, in Denver, Arapahoe, Colorado, United States, at the age of 74, and was buried in Elmwood Cemetery, Brighton, Adams, Colorado, United States.