When John Harwood Little was born on 7 June 1882, in Denver, Arapahoe, Colorado, United States, his father, Lucius Harwood Little, was 23 and his mother, Mary Evans, was 20. He married Mary B Minnie Brown on 11 February 1907, in Colorado, United States. He lived in Laramie, Albany, Wyoming, United States for about 10 years and Election District 5, Laramie, Wyoming, United States in 1940. He died on 21 March 1950, at the age of 67, and was buried in Laramie, Albany, Wyoming, United States.