When Henry Druce was born on 5 June 1820, in Merton, Surrey, England, United Kingdom, his father, John Druce, was 40 and his mother, Sophia Bragg, was 29. He married Harriet Jinks on 4 May 1845, in Manchester, Lancashire, England. They were the parents of at least 4 sons and 6 daughters. He lived in Douglas, Otoe, Nebraska, United States in 1860. He died on 12 March 1896, in Salt Lake City, Salt Lake, Utah, United States, at the age of 75, and was buried in Salt Lake City Cemetery, Salt Lake City, Salt Lake, Utah, United States.