When Andrew Jackson Jayne was born on 27 December 1845, in Flatgap, Johnson, Kentucky, United States, his father, Daniel Boone Jayne, was 43 and his mother, Savillia Nickel Jayne, was 39. He married Sarah I Howell on 7 January 1869, in Dent, Missouri, United States. They were the parents of at least 3 sons and 4 daughters. He lived in Union Township, Ste. Genevieve, Missouri, United States in 1880 and Sisson Township, Howell, Missouri, United States in 1900. He died on 11 October 1902, in Howell Township, Howell, Missouri, United States, at the age of 56, and was buried in Howell, Missouri, United States.