When Tabitha Woodson was born on 11 July 1763, in St James Northam Parish, Goochland, Virginia, British Colonial America, her father, Patrick Woodson, was 21 and her mother, Nancy Clough, was 8. She married Rene Napier on 5 January 1786, in Fluvanna, Virginia, United States. They were the parents of at least 3 sons and 1 daughter. She died about 1844, in Casey, Kentucky, United States, at the age of 81.