Paschal Byron Ayers was born in 1810, in Vermont, United States. He married Lydia Narcissa Northup about 1835, in North Hebron, Hebron, Washington, New York, United States. They were the parents of at least 3 sons and 2 daughters. He died on 25 January 1863, in Chester Township, Morrow, Ohio, United States, at the age of 53, and was buried in Chesterville Methodist Cemetery, Chesterville, Morrow, Ohio, United States.