When Bonifacio Castro was born about 1853, in Xalitzintla, San Nicolás de los Ranchos, Puebla, Mexico, his father, Toribio Castro, was 17 and his mother, Maria Felipa Mejía, was 13. He married María Rosa de Aquino Morales on 23 October 1884, in San Nicolás de los Ranchos, Puebla, Mexico. They were the parents of at least 2 sons and 1 daughter. He died on 7 October 1919, in his hometown, at the age of 66.