When Hiram Spofford was born on 28 February 1800, in Bingham, Somerset, Maine, United States, his father, Amherst Spofford, was 32 and his mother, Hannah Emerson, was 28. He married Belinda Russell on 13 March 1823, in Bingham, Somerset, Maine, United States. They were the parents of at least 5 sons and 6 daughters. He lived in Brighton, Somerset, Maine, United States in 1850. He died on 1 August 1875, at the age of 75, and was buried in Brighton, Somerset, Maine, United States.