When John Vosburgh was born on 29 August 1798, in Sheffield, Berkshire, Massachusetts, United States, his father, Isaac Vosburgh Jr., was 38 and his mother, Nancy Kellogg, was 37. He married Betsey B. Fillmore in 1822, in Walworth, Wayne, New York, United States. They were the parents of at least 4 sons and 3 daughters. He lived in Perrysburg, Perrysburg, Cattaraugus, New York, United States for about 10 years and New York, United States in 1870. He died on 28 February 1872, at the age of 73, and was buried in Pine Hill Cemetery, Gowanda, Collins, Erie, New York, United States.