When Jesse Clifton Lowry was born on 28 August 1885, in Edgefield, Edgefield, South Carolina, United States, his father, James Conrad Lowry, was 35 and his mother, Virginia Caroline "Jennie" Ouzts, was 32. He married Martha Curtis Crouse on 31 May 1914, in Greenwood, Greenwood, South Carolina, United States. They were the parents of at least 4 sons. He lived in North Carolina, United States in 1976 and Chester, Chester, South Carolina, United States in 1978. He died on 8 November 1978, in Charlotte, Mecklenburg, North Carolina, United States, at the age of 93, and was buried in Chester, South Carolina, United States.