When Reuben Samuel Hughes was born on 18 May 1907, in Joaquin, Shelby, Texas, United States, his father, James Samuel Hughes, was 32 and his mother, Bessie Rena Greene, was 26. He had at least 1 daughter with Ovella Pearl Simpson. He lived in Justice Precinct 4, Shelby, Texas, United States in 1910 and Justice Precinct 7, Shelby, Texas, United States in 1920. He died in November 1974, in Jacksonville, Cherokee, Texas, United States, at the age of 67.