When Jesse Holister Quackenbush was born on 15 August 1825, in Fultonville, Glen, Montgomery, New York, United States, his father, Abraham N. Quackenbush, was 31 and his mother, Eveline Wemple, was 29. He married Almira Lytle on 3 August 1845, in Ann Arbor, Washtenaw, Michigan, United States. They were the parents of at least 1 son and 4 daughters. He lived in East Saginaw, Saginaw, Michigan, United States in 1880 and Saginaw, Saginaw, Michigan, United States in 1900. He died on 20 April 1902, in South Saginaw, Saginaw, Michigan, United States, at the age of 76.