When Ernest George Poeppelmeyer was born on 21 February 1881, in Warren, Missouri, United States, his father, Simon Ernst August Poeppelmeier, was 28 and his mother, Wilhelmina Friederika Knapheide, was 21. He married Eleanor Dreyer on 5 April 1911, in Warren, Missouri, United States. He lived in Palmyra, Marion, Missouri, United States in 1916 and Elkhorn township, Warren, Missouri, United States for about 10 years. He died on 22 May 1952, in Warrenton, Warren, Mississippi, United States, at the age of 71, and was buried in Warrenton City Cemetery, Warrenton, Warren, Missouri, United States.