When Samuel Franklin Toole was born on 13 July 1883, in Knox, Tennessee, United States, his father, William Toole, was 52 and his mother, Sarah Virginia Kinsey, was 35. He married Clyde Florence Sampson on 24 September 1904, in Knox, Tennessee, United States. They were the parents of at least 1 son and 1 daughter. He lived in Knoxville, Knox, Tennessee, United States for about 20 years and Civil District 8, Knox, Tennessee, United States in 1940. He died on 21 April 1965, at the age of 81, and was buried in Knoxville, Knox, Tennessee, United States.