When Susanna Talkington was born about 1725, in Surry, North Carolina, British Colonial America, her father, John Robert Talkington, was 22 and her mother, Jane Elizabeth James, was 19. She married John Michael Shugart in February 1746, in Holy Trinity Church, New Castle, Delaware, British Colonial America. They were the parents of at least 5 sons and 1 daughter. She died on 24 June 1811, in Orange, North Carolina, United States, at the age of 86.