When Mary Bigelow was born on 18 September 1748, in Shrewsbury, Worcester, Massachusetts Bay Colony, British Colonial America, her father, Joseph Bigelow, was 45 and her mother, Martha Brigham, was 43. She married Isaac Moore Jr on 24 June 1768, in Shrewsbury, Worcester, Massachusetts Bay Colony, British Colonial America. They were the parents of at least 5 sons and 9 daughters. She died on 23 February 1825, in Berlin, Worcester, Massachusetts, United States, at the age of 76, and was buried in Old Burying Ground, Holden, Worcester, Massachusetts, United States.