When Susanna Overholt was born on 27 September 1803, in Westmoreland, Pennsylvania, United States, her father, Martin Beidler Overholt, was 30 and her mother, Catharine Overholt, was 21. She had at least 3 sons and 3 daughters with Henry Shupe. She lived in South Huntingdon Township, Westmoreland, Pennsylvania, United States for about 30 years. She died on 2 September 1885, in East Huntingdon Township, Westmoreland, Pennsylvania, United States, at the age of 81, and was buried in Hoffman Cemetery, South Huntingdon Township, Westmoreland, Pennsylvania, United States.