When Nancy Mary Watson was born on 9 September 1864, in Levy, Florida, United States, her father, Franklin K Watson, was 31 and her mother, Missouri Ann Clark, was 31. She married James Washington Billups on 10 April 1888, in Bronson, Levy, Florida, United States. They were the parents of at least 3 sons and 4 daughters. She lived in Bronson, Levy, Florida, United States in 1900 and Morriston, Levy, Florida, United States in 1910. She died on 17 March 1934, in Brooksville, Hernando, Florida, United States, at the age of 69, and was buried in Brooksville Cemetery, Brooksville, Hernando, Florida, United States.