When Henry Miller was born in 1793, in Lincoln, North Carolina, United States, his father, John Miller, was 36 and his mother, Martha Kathrine Clay, was 30. He married Elizabeth Cooper in 1816, in Cape Girardeau, Missouri, United States. They were the parents of at least 8 sons and 3 daughters. He died on 5 November 1849, in Millersville, Cape Girardeau, Missouri, United States, at the age of 56, and was buried in Millersville, Cape Girardeau, Missouri, United States.