When Dr. Thomas Oliver McCallie was born on 28 September 1868, in Sevier, Tennessee, United States, his father, Andrew Jackson McCallie, was 48 and his mother, Harriet Theodoshia Athaline Cunningham, was 43. He married Cora Belle Jones about 1886, in Tennessee, United States. They were the parents of at least 4 sons and 1 daughter. He lived in Civil District 3, Knox, Tennessee, United States in 1910 and Knoxville, Knox, Tennessee, United States in 1920. He died on 13 December 1924, at the age of 56.