When Audubon Spencer Alvis was born on 3 July 1855, in Lee, Iowa, United States, his father, Henry Jefferson Alvis, was 43 and his mother, Electa Daniels, was 34. He married Laura Ellen Good in 1875, in Alexandria, Clark, Missouri, United States. They were the parents of at least 3 sons and 6 daughters. He lived in Des Moines Township, Lee, Iowa, United States for about 20 years and La Plata, Macon, Missouri, United States in 1910. He died on 18 February 1920, in Keokuk, Lee, Iowa, United States, at the age of 64, and was buried in Keokuk, Lee, Iowa, United States.