When Mary Prentice was born in 1716, in Newton, Massachusetts Bay Colony, British Colonial America, her father, John Prentice, was 25 and her mother, Elizabeth Hall, was 19. She married Nathanial Luce on 25 December 1735, in Windham, Connecticut Colony, British Colonial America. They were the parents of at least 1 son and 2 daughters. She died about 1750, in Connecticut Colony, British Colonial America, at the age of 34.