When David Spalding was born on 25 August 1793, in Hoosick, Rensselaer, New York, United States, his father, Elijah Spalding, was 48 and his mother, Deborah Scribner, was 43. He married Sarah or Sally Van Boskark on 29 December 1815. They were the parents of at least 5 sons and 4 daughters. He lived in Darien, Genesee, New York, United States in 1850 and Aurora, Erie, New York, United States for about 10 years. He died on 28 August 1872, in New York, United States, at the age of 79, and was buried in Holland, Holland, Erie, New York, United States.