When Edson Benjamin Ambrose was born on 1 January 1863, in Delaware, Ohio, United States, his father, William A. Ambrose, was 28 and his mother, Delia A. Manter, was 30. He married Rosetta Mae Garrett on 3 July 1886, in Marion, Marion, Ohio, United States. They were the parents of at least 4 sons and 2 daughters. He lived in Ohio, United States in 1870 and Marion, Marion Township, Marion, Ohio, United States for about 20 years. He died on 13 August 1947, in Marion, Marion, Ohio, United States, at the age of 84, and was buried in Chapel Heights Memorial Gardens, Bellaire Gardens, Marion, Ohio, United States.