When Eliza Heart was born on 13 September 1828, in McMinn, Tennessee, United States, her father, John Hart, was 39 and her mother, Ruth Stout, was 33. She married Thomas Languard Murphy on 6 March 1845, in Greene, Missouri, United States. They were the parents of at least 10 sons and 2 daughters. She lived in Empire City, Galena, Cherokee, Kansas, United States in 1880 and Garfield, Benton, Arkansas, United States in 1900. She died on 11 March 1907, in Benton, Arkansas, United States, at the age of 78.