When Harrison Bobbitt was born on 20 April 1810, in Rutherford, Tennessee, United States, his father, John Preston Bobbitt, was 21 and his mother, Nancy Huse Hughes, was 17. He married Lydia Boswell on 15 November 1832, in Orange, Indiana, United States. They were the parents of at least 1 son and 2 daughters. He lived in Southeast Township, Orange, Indiana, United States for about 20 years and Indiana, United States in 1870. He died on 10 January 1876, at the age of 65, and was buried in Valeene, Southeast Township, Orange, Indiana, United States.