When Mildred Meriwether was born on 29 December 1757, in St James Northam Parish, Goochland, Virginia, British Colonial America, her father, Cap. William Meriwether, was 27 and her mother, Martha Cox Wood, was 25. She married Thomas Mitchell on 24 July 1775, in Louisa, Virginia, United States. They were the parents of at least 1 son and 1 daughter. She died in 1782, in Louisa, Virginia, United States, at the age of 25.