When Simeon O'Dell was born about 1755, in Greenwich, Greenwich, Washington, New York, United States, his father, Simeon Odell, was 33 and his mother, Mary Morey, was 30. He married Elizabeth Brinker about 1780. They were the parents of at least 8 sons and 4 daughters. He died in 1820, in his hometown, at the age of 65.