When Robert Rose was born in 1806, in Sullivan, Tennessee, United States, his father, Reuben Rose, was 27 and his mother, Martha Patricia Mason, was 25. He married Mahala Guinn Stark in 1828, in Robertson, Tennessee, United States. They were the parents of at least 4 sons and 5 daughters. He lived in Robertson, Tennessee, United States in 1850. He died on 18 December 1860, in Pike, Missouri, United States, at the age of 54.