When Michael Rudisill was born on 11 December 1789, in Codorus Township, York, Pennsylvania, United States, his father, Johann Ludwig Rudisill, was 49 and his mother, Magdalena Trone, was 40. He married Catharine Krumrein on 14 June 1810, in Hanover, York, Pennsylvania, United States. They were the parents of at least 4 sons and 3 daughters. He died on 8 November 1823, in Spring Grove, York, Pennsylvania, United States, at the age of 33, and was buried in Saint Peters Church Cemetery, Seven Valleys, York, Pennsylvania, United States.
Americanized form of Swiss German Rüdisühli or Rüedisüli, a compound of the personal names Rüdi (an Alemannic short form of Rudolf ) + Üli (from Ulrich ) with the connecting patronymic suffix -s.