When Oma Elizabeth Isom was born on 14 May 1881, in Virginia, United States, her father, Archibald Ison, was 34 and her mother, Mary A Parker, was 36. She married Floyd Delaney Penley on 26 June 1920, in Washington, Tennessee, United States. They were the parents of at least 1 son and 2 daughters. She lived in Civil District 7, Hawkins, Tennessee, United States in 1910 and Kingsport, Sullivan, Tennessee, United States in 1930. She died on 14 March 1953, at the age of 71, and was buried in Gunnings Cemetery, Gunnings, Sullivan, Tennessee, United States.