When Irena Sophronia Summers was born about 1838, in Missouri, United States, her father, Moses Summers, was 26 and her mother, Celia Mumford Gilstrap, was 20. She married James Madison Stout on 3 December 1863, in Putnam, Missouri, United States. They were the parents of at least 3 sons and 2 daughters. She lived in Elm Township, Putnam, Missouri, United States in 1860 and Ravanna, Mercer, Missouri, United States in 1870. She died on 15 February 1872, at the age of 34.