When Calvin Hempsted was born on 12 September 1800, in Westmoreland, Shelter Island, Suffolk, New York, United States, his father, James Hempsted, was 31 and his mother, Huldah Bosworth, was 38. He married Amanda Wilcox or Wilcot about 1820, in New York, United States. They were the parents of at least 4 sons and 4 daughters. He lived in Ripley, Chautauqua, New York, United States in 1850 and Spring Prairie, Walworth, Wisconsin, United States for about 20 years. He died on 3 September 1892, in Walworth, Wisconsin, United States, at the age of 91, and was buried in Hickory Grove Cemetery, Spring Prairie, Walworth, Wisconsin, United States.