When Irene Eliza Daugherty was born on 28 June 1857, in Jersey, Illinois, United States, her father, John George Dougherty, was 36 and her mother, Susan Millross, was 31. She married Dr. Charles Alfred Lee Reed on 27 May 1880, in Jerseyville, Jersey, Illinois, United States. They were the parents of at least 2 sons and 1 daughter. She lived in Illinois, United States in 1870 and Cincinnati, Hamilton, Ohio, United States for about 10 years. She died in 1915, in Hamilton, Butler, Ohio, United States, at the age of 58.