When Richard Pile Jr was born on 14 December 1764, in Hardesty, Prince George's, Maryland, United States, his father, Richard Pile, was 38 and his mother, Elizabeth Sprigg, was 36. He married Rebecca Clifton on 15 January 1792, in Nelson, Kentucky, United States. They were the parents of at least 3 sons and 4 daughters. He died on 23 March 1816, in Jeffersonville, Clark, Indiana, United States, at the age of 51, and was buried in Jeffersonville, Clark, Indiana, United States.