When Ephraim Shroyer was born on 3 June 1835, in Mount Pleasant, Henry, Iowa, United States, his father, William Shroyer, was 32 and his mother, Elenor Waggoner, was 36. He married Mary Jane Cotterill on 4 March 1856, in Mount Pleasant, Henry, Iowa, United States. They were the parents of at least 8 sons and 1 daughter. He lived in Mad River Township, Montgomery, Ohio, United States for about 20 years. He died on 30 September 1897, in Dayton, Montgomery, Ohio, United States, at the age of 62, and was buried in Dayton, Montgomery, Ohio, United States.