When Nancy Malissa Bobo was born on 1 February 1847, in Hart, Georgia, United States, her father, Thomas Mahlon Bobo, was 28 and her mother, Louisa Catherine Hudson Crump, was 21. She married John Middleton Reynolds on 20 December 1866, in Hart, Georgia, United States. They were the parents of at least 4 sons and 3 daughters. She lived in District 1112, Hart, Georgia, United States for about 30 years. She died on 1 May 1921, in Hart, Georgia, United States, at the age of 74, and was buried in Hartwell, Hart, Georgia, United States.