When Laura F. Willson was born on 23 December 1826, in Fairfax, Franklin, Vermont, United States, her father, Amos Willson, was 27 and her mother, Elizabeth P. Wright, was 19. She married Allen McKain on 22 March 1846. They were the parents of at least 6 sons and 3 daughters. She lived in Michigan, United States in 1870 and Pavilion, Kalamazoo, Michigan, United States in 1880. She died on 9 January 1892, in Pavilion Township, Kalamazoo, Michigan, United States, at the age of 65, and was buried in Pavilion Township, Kalamazoo, Michigan, United States.