When Amasa Spencer Kneeland was born on 22 October 1815, in Thorn Hill, Marcellus, Onondaga, New York, United States, his father, Amasa K Kneeland, was 39 and his mother, Charlotte Kidder, was 28. He married Almira Barnes Foote about 1840, in Clinton, Kirkland, Oneida, New York, United States. They were the parents of at least 2 sons and 2 daughters. He lived in Franklinville, Franklinville, Cattaraugus, New York, United States in 1875 and Sandusky, Freedom, Cattaraugus, New York, United States in 1880. He died on 12 May 1892, at the age of 76, and was buried in Knox, Illinois, United States.